A1,
A2,
B,
C1,
C2,
D,
E,
F,
G-H,
I-K,
L,
M,
N,
O,
P1,
P2,
Q-R,
S,
T,
U-V,
W-Z
Nasalcrom Online, Description, Chemistry, Ingredients - Cromolyn Sodium
Nasalcrom Online, Description, Chemistry, Ingredients - Cromolyn Sodium
DESCRIPTION
Chemically, cromolyn sodium
is the disodium salt of
1,3-bis (2-carboxychromon-5-yloxy)-2-hydroxypropane. The empirical
formula is C23H14Na2O11;
the molecular weight
is 512.34.
Gelatin Capsules
Each gelatin capsule
of Gastrocrom (cromolyn sodium,
USP) contains 100 mg cromolyn sodium. Cromolyn sodium
is a hygroscopic, white
powder having little
odor. It may leave a slightly bitter
aftertaste. It is soluble
in water (1 proof in 20)
and the resulting solution
is neutral. It is intended for oral
use.
Pharmacologic Category: Mast cell
stabilizer
Therapeutic Category: Antiallergic
Capsules for Inhalation, Inhalation Aerosol, and Inhalation
Solution
The active ingredient
is cromolyn sodium, USP.
It is an inhaled anti-inflammatory agent for the preventive
management of asthma. Cromolyn sodium
is a water-soluble, odorless, white, hydrated
crystalline powder.
It is tasteless at first, but leaves a slightly bitter
aftertaste.
Capsules for Inhalation: Each cromolyn sodium
for inhalation capsule contains 20 mg
cromolyn sodium and 20
mg lactose. The contents
of the capsule are intended
for inhalation use
only, with the Spinhaler turbo-inhaler.
Inhalation Aerosol: Cromolyn sodium
Inhaler is a metered dose aerosol unit
for oral inhalation
containing micronized cromolyn sodium, sorbitan trioleate with dichlorotetrafluoroethane
and dichlorodifluoromethane as propellants. Each metered inhalation
delivers approximately 800 mcg cromolyn sodium
through the mouthpiece to the patient. Each 8.1 g canister delivers
at least 112 metered inhalations (56 doses); each 14.2 g canister
delivers at least 200 metered inhalations (100 doses).
Inhalation Solution: Cromolyn sodium
inhalation solution
is clear, colorless, sterile,
and has a target pH
of 5.5.
Each 2 ml ampule
of Intal Nebulizer Solution contains 20 mg
cromolyn sodium, USP, in purified water.
Nasal Solution
Each milliliter
of Nasalcrom Nasal Solution contains 40 mg
cromolyn sodium in purified water
with 0.01% benzalkonium chloride
to preserve and 0.01% EDTA
(edetate disodium) to stabilize the solution. Cromolyn sodium nasal
solution possesses
a natural pH
of 4.5-6.5 and negligible titratable acidity.
Pharmacologic Category: Mast cell
stabilizer/antiallergic.
Therapeutic Category: Antiallergic.
After priming the delivery
system for Nasalcrom, each
actuation of the unit delivers a metered spray
containing 5.2 mg of cromolyn sodium. The contents of one bottle delivers
at least 100 sprays (13 ml bottle)
or 200 sprays (26 ml bottle).
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