A1,
A2,
B,
C1,
C2,
D,
E,
F,
G-H,
I-K,
L,
M,
N,
O,
P1,
P2,
Q-R,
S,
T,
U-V,
W-Z
Celexa Online, Description, Chemistry, Ingredients - Citalopram
Celexa Online, Description, Chemistry, Ingredients - Citalopram
DESCRIPTION
Celexa™ (citalopram HBr) is an orally administered selective
serotonin reuptake inhibitor (SSRI) with a chemical structure unrelated to that
of other SSRIs or of tricyclic, tetracyclic, or other available antidepressant
agents. Citalopram HBr is a racemic bicyclic phthalane derivative designated
(±)-1-(3-dimethylaminopropyl)-1- (4-fluorophenyl)-1,3-dihydroisobenzofuran -5-carbonitrile,
HBr with the following structural formula:
The molecular formula is C20H22BrFN2O
and its molecular weight is 405.35.
Citalopram HBr occurs as a fine, white to off-white powder.
Citalopram HBr is sparingly soluble in water and soluble in ethanol.
Celexa (citalopram hydrobromide) is available as tablets or
as an oral solution.
Celexa 10 mg tablets are film-coated, oval tablets containing
citalopram HBr in strengths equivalent to 10 mg citalopram base. Celexa 20 mg
and 40 mg tablets are film-coated, oval, scored tablets containing citalopram
HBr in strengths equivalent to 20 mg or 40 mg citalopram base. The tablets also
contain the following inactive ingredients: copolyvidone, corn starch, crosscarmellose
sodium, glycerin, lactose monohydrate, magnesium stearate, hypromellose, microcrystalline
cellulose, polyethylene glycol, and titanium dioxide. Iron oxides are used as
coloring agents in the beige (10 mg) and pink (20 mg) tablets.
Celexa oral solution contains citalopram HBr equivalent to
2 mg/mL citalopram base. It also contains the following inactive ingredients:
sorbitol, purified water, propylene glycol, methylparaben, natural peppermint
flavor, and propylparaben.
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