A1,
A2,
B,
C1,
C2,
D,
E,
F,
G-H,
I-K,
L,
M,
N,
O,
P1,
P2,
Q-R,
S,
T,
U-V,
W-Z
Ceftin Online, Description, Chemistry, Ingredients - Cefuroxime Axetil
Ceftin Online, Description, Chemistry, Ingredients - Cefuroxime Axetil
DESCRIPTION
Ceftin tablets and Ceftin for oral
suspension contain cefuroximine
as cefuroximine axetil. Cefuroxime axetil is a semisynthetic, broad-spectrum
cephalosporin antibiotic
for oral administration.
Chemically, cefuroxime axetil, the 1-(acetyloxy) ethyl
ester of cefuroxime, is (RS)-1-hydroxyethyl
(6R,7R)-7-[2-(2-furyl)glyoxylamido]-3-(hydroxymethyl)-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate,
72-(Z)-(O-methyl-oxime),1 -acetate 3-carbamate.
Its molecular formula is C20H22N4O10S,
and it has a molecular weight
of 510.48.
Cefuroxime axetil is in the amorphous form.
Ceftin tablets are film-coated and contain the equivalent
of 125, 250, or 500 mg of cefuroxime as cefuroxime axetil. Ceftin tablets
contain the inactive ingredients colloidal silicon
dioxide, croscarmellose sodium, FD&C blue
no. 1 (250-and 500-mg tablets only), hydrogenated vegetable oil, hydroxypropyl
methylcellulose, methylparaben, microcrystalline
cellulose, propylene glycol, propylparaben, sodium
benzoate (125-mg tablets
only), sodium lauryl sulfate, and titanium
dioxide.
Ceftin for oral suspension,
when reconstituted with water, provides the equivalent
of 125 mg or 250 mg of cefuroxime (as cefuroxime axetil) per 5 ml
of suspension. Ceftin powder
for oral suspension
contains the inactive ingredients povidone
K30, stearic acid, sucrose, and tutti-frutti flavoring.
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